From Wikipedia, the free encyclopedia
Pharmacological gene therapy is a new field that combines
pharmacological therapy and
gene therapy. It is used either to prevent a defective gene from
producing its protein or to increase the concentration of normal
protein produced in the body by insertion of DNA or RNA fragments.
It can also be using to generate immunity from contagious disease,
such as TB, via the process of DNA vaccination.
Gene Therapeutics can be used to treat such conditions as
Cystic Fibrosis (via the addition of a normal CFTR gene),
Haemophilia A or even some of the complications of
AIDS.
It uses a number of methods including:
Gene
augmentation Targeted Inhibition (using Antisense or
antigene technology) Cell Killing (either direct or assisted)
and DNA
vaccination . |